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Title
Synthesis and characterization of new 5-substituted 1H-tetrazoles in water: a greener approach
Type of Research Article
Keywords
Green chemistry, Tetrazoles, Knoevenagel Condensation, 1,3 Dipolar cycloaddition.
Abstract
In energetic materials research, much effort has been devoted to the development of environmentally benign, “green” energetic materials. Tetrazoles are readily accessible nitrogen-rich energetic compounds. Herein, we would like to report a novel, facile, eco-friendly and one-pot process for synthesis of 5-substituted 1H-tetrazoles via a domino Knoevenagel condensation and 1, 3 dipolar cycloaddition reactions. This general protocol provides 5-substituted 1H-tetrazoles in good yields under mild reaction conditions. These tetrazoles were characterized by FT-IR and 1H-NMR, 13C-NMR spectroscopy and thermogravimetric analysis.
Researchers Mehrdad Mahkam (First Researcher)، Zeinab Namazifar (Second Researcher)، mehdi nabati (Third Researcher)، Javad Aboudi (Fourth Researcher)