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Abstract
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The ability to analytically detect l-tyrosine is
a clinical necessity not only for the diagnosis of some diseases
such as tyrosinemia, but also for the study on various
tyrosine-associated disorders. In here, graphene quantum
dot (GQD) was synthesized by carbonization of
citric acid and used to prepare GQD-RuCl3 nano-composite.
GQD and GQD-RuCl3 were characterized by Fourier
transform infrared (FTIR) and Transmission electron
microscopy (TEM). Next the nano-composite was modified
with carbon-composite electrode (CCE) and the electrochemical
properties of GQD-RuCl3 jCCE were studied
by cyclic voltammetry (CV). This bulk modified electrode
showed good electrocatalytic activity for l-tyrosine oxidation.
The values of the detection limit and sensitivity
were obtained as 0.23 mM and 90 nA/mM. The results indicated
that the synergistic incorporation of RuCl3 with
GQD conspicuously promotes the sensitivity of the
sensor. Moreover, the sensor showed long-term stability
and good selectivity towards the detection of l-tyrosine.
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