Research Specifications

Asthma and COPD are inflammatory lung diseases that are characterized by chronic localized inflammation and oxidative stress. The exact cause of asthma is not known yet. Also, asthma is a complex syndrome with many clinical phenotypes that multiple factors such as autonomic system, immunology, infections, endocrine psychological agents and antioxidant/oxidant balance status play an important role in the development of the disease. Sources of oxidative stress arise from the increased burden of inhaled oxidants, as well as elevated amounts of ROS released from inflammatory cells. Dietary has main effect in pathophysiology of this problem. Food safety and suitable dietary are the most important methods to control and treatment of diseases. Antioxidant supplements have central role to alter the cellular redox milieu of immune cells and inflammatory load in the lung. The aim of this study is to highlight importance of four nonenzymatic antioxidant compounds (including glutathione, ascorbate, flavonoids, tocopherols and Polyphenols precursors) in supplement and their benefits on allergic asthma. Therefore, high protection against of asthma could be given with safe dietary