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Abstract
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The CRISPR/Cas9 system is a precisely targeted bacterial defense system, used to control
invading viruses. This technology has many potential applications including genetic changes in
somatic and germ cells and the creation of knockout animals. Compared to other genome editing
techniques such as zinc-finger nucleases and transcription activator-like effector nucleases
(TALENS), the CRISPR/Cas9 system is much easier and more efficient. Most importantly, the
multifunctional capacity of this technology allows simultaneous editing of several genes. The
CRISPR/Cas9 system also potentially has the ability to prevent and treat human diseases. The
present article addresses some key points related to the use of the CRISPR/Cas9 system as a
powerful tool in cardiovascular research and as a new strategy for the treatment of cardiovascular
disease (CVD).
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