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Title
Porous conductive and biocompatible scafolds on the basis of polycaprolactone and polythiophene for scafolding
Type of Research Article
Keywords
Star-like copolymer · Polythiophene · Polycaprolactone · Nanofber · Tissue engineering
Abstract
The fabrication of novel scafolds was represented on the basis of conductive and biodegradable copolymers. The star-like polycaprolactone (S-PCL) was synthesized from dipentaerythritol as a core by a catalyst of Sn(oct)8 through ring-opening technique. After functionalization of S-PCL by thiophene, thiophene monomer was polymerized from polycaprolactone ends via chemical oxidation polymerization to reach star-like polycaprolactone–polythiophene (S-PCL–PTh). The scafolds demonstrated a porous confguration (160–190 nm) having the great surface area as well as conductivity of 0.011 S cm−1. The cytocompatibility measurements exhibited that the nanofbers were not toxic to the MG63 cells.
Researchers Raana Sarvari (First Researcher)، Bakhshali Massoumi (Second Researcher)، Amir Zareh (Third Researcher)، Younes Beygi khosrowshahi (Fourth Researcher)، Samira Agbolaghi (Fifth Researcher)