|
Keywords
|
delivery system, nanomaterial loading, nanotechnology, plant virus, virus like particles
|
|
Abstract
|
Nanoparticles have unique capabilities and considerable promise for many different
biological uses. One capability is delivering bioactive cargos to specific
cells, tissues, or organisms. Depending on the task, there are multiple variables
to consider including nanoparticle selection, targeting strategies, and incorporating
cargo so it can be delivered in a biologically active form. One nanoparticle
option, genetically controlled plant viral nanoparticles (PVNPs), is highly
uniform within a given virus but quite variable between viruses with a broad
range of useful properties. PVNPs are flexible and versatile tools for incorporating
and delivering a wide range of small or large molecule cargos. Furthermore,
PVNPs can be modified to create nanostructures that can solve
problems in medical, environmental, and basic research. This review discusses
the currently available techniques for delivering bioactive cargos with PVNPs
and potential cargos that can be delivered with these strategies.
|