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Title
Preparation and characterization of electrospun shape memory polyurethane/graphene quantum dot nanocomposite scaffolds for tissue engineering
Type of Research Article
Keywords
Electrospinning; GQD nanoparticles; shape memory polyurethane; 3T3 fibroblast cell 1. Introduction Nowadays, skin treatment of patients suffering from skin injuries such as diabetic ulcer, burn, and melanoma skin cancer is of a great importance. Recent studies suggest that tissue engineering, which consider the interactions of extracellular matrix (ECM), growth factor, and cell to fabricate new biological
Abstract
Shape memory polyurethane (SMPU)/graphene quantum dot nanoparticles (GQDs) nanofibers were prepared by electrospinning technique. Results show that the localization of GQD nanoparticles into the nanocomposite electrospun nanofibers has increased the nanofiber average diameter. An increment has been observed in the mechanical strength of nanocomposite nanofiber mats. More uniform and straight nanofibers have been obtained for PU-0.5% due to the relative electrical conductivity induced by the presence of GQD nanoparticles. Presence of crystallizable polycaprolactone (PCL) soft segment in PU structure induced shape memory potential in electrospun scaffolds. In vitro study showed PU-0.5% scaffold had good interaction with 3T3 fibroblast cells.
Researchers (First Researcher)، - - (Second Researcher)، Mostafa Rezaei (Third Researcher)، Massoumeh Bagheri (Fourth Researcher)، Amin Babaei (Fifth Researcher)، (Not In First Six Researchers)