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Keywords
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Adamantane motif, Diamondoid, Biginelli reaction, 3,4-Dihydropyrimidin-2(1H)-thione, β-Keto amide
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Abstract
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Novel dihydropyrimidines incorporating an adamantane motif have been synthesized using a three-component Biginelli reaction of adamantane-containing β-keto amide N-1-adamantyl acetoacetamide as active methylene compound, thiourea, and aromatic aldehydes in more convenient condition and high yields. The structures of the synthesized compounds were confirmed by spectral data.
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