|
Abstract
|
Despite the huge advances in analytical instruments in the past decades, the sample preparation is still considered as the most vital step in all analytical processes. Sample preparation is the main source of systematic errors and random inaccuracies in analytical methods. Therefore, the main objectives of sample preparation are the reproducible separation of the target analytes from the matrix, with the aim of reducing the effects of the matrix in the measurement phase.Microextraction is considered as one of the most critical steps in the entire analytical process because it can effectively remove interference and pre-concentrate the target analytes. In recent years, there has been a growing awareness of the importance of the extraction technology in the analytical process, especially for analytes present in complex samples. Molecular imprinting is known as a technique for creation of tailor-made binding sites with memory of the shape, size and functional groups of the template molecules.Compared to other recognition systems, MIPs possess many promising characteristics, such as low cost and easy synthesis, high stability to harsh chemical and physical conditions, and excellent reusability. The determination of the naproxen concentration, a widely utilized non-steroidal anti-inflammatory drug (NSAID), in various real samples necessitates the implementation of efficient analytical methods due to the drug's ubiquitous presence and potential environmental impact.
|