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Abstract
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The thyroid gland, a small, butterfly-shaped gland located at the base of the neck below the Adam's apple, produces two primary hormones: thyroxine (T-4) and triiodothyronine (T-3). These hormones influence every cell in the body, regulating the use of fats and carbohydrates, controlling body temperature, affecting heart rate, and modulating protein synthesis. When the thyroid gland doesn't make enough thyroid hormone, it leads to hypothyroidism. This condition also is called underactive thyroid. Hypothyroidism may not cause noticeable symptoms in its early stages. For the body's metabolism to remain balanced, thyroid hormones play a critical physiological role. The goal of this research is to look into the relationship between GFAP, T3, T4, and TSH levels in Baghdad patients with hypothyroidism. It aims to analyze Glial fibrillary acidic protein (GFAP)'s potential as a biomarker, comprehend the fundamental causes of the disease, and provide information for improved diagnosis and treatment. It also concentrates on determining any local characteristics that may influence hypothyroidism in this particular community. In short, studying the relationship between chemical parameters and hypothyroidism is not only essential for a deeper understanding of the health condition, but also plays a crucial role in improving health care and developing appropriate treatment and prevention strategies. Biochemical factors including thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) levels can help with hypothyroidism diagnosis and monitoring. Understanding the relationships between these hormones and other biochemical markers may assist in the identification of subclinical or atypical forms of hypothyroidism that would otherwise go undetected.
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