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Abstract
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The escalating incidence of kidney failure worldwide necessitates urgent exploration of effective therapeutic strategies to mitigate its progression and improve patient outcomes. As renal diseases increasingly become a leading cause of morbidity and mortality, understanding the underlying mechanisms of damage and identifying potential treatments are paramount. Oxidative stress plays a crucial role in renal impairment, leading to cellular dysfunction and tissue damage. Given the complexity of kidney failure and the limitations of current treatment options, research into antioxidant therapies, such as N-Acetylcysteine (NAC), provides a promising avenue for intervention. NAC’s potential to replenish glutathione levels and reduce oxidative damage positions it as a candidate for therapeutic exploration. Furthermore, a deeper understanding of NAC's role in reducing serum creatinine (Scr) levels and improving kidney function through non-invasive markers is vital. These insights could significantly influence clinical practice, offering new approaches to manage kidney failure and enhance the quality of life for patients. In summary, this research topic is of critical importance not only for advancing scientific knowledge but also for informing clinical strategies that may slow the progression of kidney failure, ultimately leading to better patient care and outcomes.
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