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Title
Global dynamics of a multi-stage fractional HIV-infected model with general incidence rate and drug efficacy
Type of Research Article
Keywords
Viral infection, Multi-stage infection, Caputo fractional derivative, Lyapunov functional, Stability
Abstract
‎For several decades researchers have been studying global dynamics of viral infection models to prevent wide outbreak of scattered virus both in population and vivo such as Dengue fever‎, ‎SARS-COV2‎, HRSV, ‎and immunodeficiency diseases‎. ‎In this paper‎, ‎our main aim is obtaining sufficient conditions for the global stability of equilibria of a Caputo fractional derivative order system with general incidence functional response by using Lyapunov ‎method and LaSalle's invariance principle‎. ‎We prove the global stability of stationary points by the values of the basic reproduction number {R_0} and we consider this threshold as a strong index for our sensitivity analysis‎‎. ‎We confirm theoretical results through numerical simulations.‎
Researchers Marouane Mahrouf (First Researcher)، Fereshteh Keshavarz (Second Researcher)