مشخصات پژوهش

Rheum ribes, a perennial plant of polygonaceae family, is native to asia. It has been growing in Europe since the 16th century chrysophanol and other anthraqinone derivative were isolated from the root and areal parts of Rheum ribes. Chrysophanol and its derivatives are active compounds as anti-inflammatory, anti-bacterial and anti-viral. In this study triethylsilyl and tert-buthyldimethylsilyl derivative of chrysophanol were synthesized [1-2]. Alcohol readily reacts with compounds such as trimethylchlorosilane and base to turnedmethylsilylether, and in contact with water become primary alcohol andsilanol. Silicon derivatives synthesis was carried out as follows, Dry Tetrahydrofuran (THF) was the solvent used in the synthesis and tri-ethyl amine (ET3N) as a bases. The reaction mixture was refluxed for 24hours under argon gas at room temperature.The solvent was filtered and evaporated under reduced pressure.