مشخصات پژوهش

Today, medicinal plants play a very important role in human health. Plants can be considered as a valuable source of a wide variety of secondary compounds [1]. Many medicinal plants contain large amounts of antioxidant compounds, such as polyphenols, which can play an important role in absorbing and neutralizing free radicals [2, 3]. Eryngium caucacicum L. is a well-known medicinal plant belonging to the family Apiaceae. This biennial herb is used as food in Iran, Turkey, Kosovo, Spain, and Italy. It possesses numerous biological and pharmacological activities such as antibacterial, antifungal, antioxidant, antiinflammatory, antitumor activities [4]. In this study, after collection of the roots and leaves of Eryngium caucacicum from North of Iran, the methanol and ethyl acetate extracts were obtained, and then, their antioxidant potential and total phenol and flavonoid contents were investigated. The antioxidant potential was studied using DPPH assay and the total phenolic content was determined quantitatively using the Folin Ciocalteu reagent, with Gallic acid as the standard. Also, total flavonoid content was estimated using aluminum chloride method. The findings showed that the leaves methanol extracts had the highest total phenolic and flavonoid contents, and their values were equal to 70.94 , and 35.62 mg/g extract, respectiely. Also, the antioxidant study indicated that the roots ethanolic and ethyl acetate extracts significantly exhibited antioxidant potential with IC50 values of 88.36, 112.92 µg/mL, respectively. So, the results of this study could provide useful information to guide the application of Eryngium caucacicum parts in food and pharmaceutical fields.