مشخصات پژوهش

Covalent organic frameworks (COFs) are a class of crystalline porous polymer that allows the precise integration of organic units into extended structures at an atomic level [1]. The fascinating structures and unique properties such as large surface area, abundant functional group and high chemical stability make COFs attractive materials in the fields of gas adsorption, separation, catalysis, optoelectronic devices and sensors [2, 3]. In this work, a novel electrochemical platform was developed based on facile synthesis of a covalent organic framework (COF) Via in situ growth of Pt nanoparticles (PtNPs) on the surface of COFs and COFs-MWCNTs composites with improved electroactivity. After incorporation of MWCNTs into the composites, the PtNPs@COFs-MWCNTs nanocomposites that possess excellent electrocatalytic activity and unprecedented catalytic performance were formed and utilized for determination of dopamine. Under the optimum conditions, this electrochemical sensor presented excellent electrochemical properties to this biomolecule. The linear ranges for the determination of dopamine was 0.01-40 μmol/L with the correlation coefficients of 0.9905. The detection limits were 7.4 nmol/L (S/N = 3). In addition, the modified electrode was also applied to the determination of dopamine in human serum samples and the recovery were varied from 96.5% to 104.8%. Moreover, there are no significant effects from the interferents and The results demonstrated that the modified electrode had the characteristics of high sensitivity, good selectivity and reliability.