مشخصات پژوهش

Novel 4H-pyrans incorporating an adamantane moiety were synthesized by the sequential Michael addition/cyclization reaction of arylidene malononitriles and N-1-adamantyl acetoacetamide. The 2-pyrone derivatives are formed upon hydrolysis of the iminopyran intermediates resulting from the intramolecular cyclization by nucleophilic attack of the hydroxyl group on the cyano group.