مشخصات پژوهش

Skin injuries have always been considered as one of the most common health problems. Therefore, many researches have been interested in to find an efficient method for wound healing. Since hydrogels have suitable characteristics, they are widely used for this purpose. In this study, alginate and polyvinyl alcohol were selected as hydrogel matrix based on their high efficiencies in the wound healing. Also, to induced antibacterial and antioxidant properties simultaneously, zinc oxide nanoparticles and green tea extract were incorporated to hydrogels followed by evaluating their physicochemical properties. Our results indicated that the nanocomposite hydrogels have appropriate swelling degree, degradation rate and hydrophilicity to be used in wounds with high secretions. Other properties of the dressings such as antibacterial peroperties, antioxidant activity, mechanical strength, and cytocompatibility will be investigated.