مشخصات پژوهش

1,4-dihydropyridines (1,4-DHPs) are pharmacologically active compounds and are an important class of L-type calcium channel blockers utilized in the treatment of cardiovascular disorders, including hypertension, angina, and other spastic muscle disorders. As a result, 1,4-dihydropyridines (DHPs) serve as privileged pharmacophores and are attractive synthetic targets in organic chemistry. This review aims to describe various methodologies employed in the synthesis of this class of compounds.