مشخصات پژوهش

Cobalt hydroxide nanoparticles were prepared onto a carbon ceramic electrode (CHNjCCE) using the cyclic voltammetry (CV) technique. The modified electrode was characterized by X-ray diffraction and scanning electron microscopy. The results showed that CHN with a single-layer structure was uniformly electrodeposited on the surface of CCE. The electrocatalytic activity of the modified electrode toward the oxidation of insulin was studied by CV. CHNjCCE was also used in a homemade flow injection analysis system for insulin determination. The limit of detection (signal/noise [S/N] ¼ 3) and sensitivity were found to be 0.11 nM and 11.8 nA/nM, respectively. Moreover, the sensor was used for detection of insulin in human serum samples. This sensor showed attractive properties such as high stability, reproducibility, and high selectivity.